Publication of the ERA4Health partnership pilot call for clinical trials: 'Fostering Pragmatic Comparative-Effectiveness Trials in Non-communicable Diseases' (EffecTrial)'
On 21 November 2024, the Ministry of Health (hereinafter referred to as the "Ministry of Health") publishes, in accordance with Act No. 130/2002 Coll., on support for research, experimental development and innovation from public funds and on amendments to certain related acts (Act on support for research, experimental development and innovation), as amended (hereinafter referred to as the "Act"),
the ERA4Health Partnership's pilot call for clinical trials:
"Fostering Pragmatic Comparative-Effectiveness Trials in Non-communicable Diseases (EffecTrial)"
Call 2025
Basic information
Deadline for announcement of results
October 2025
National budget allocation for the call
500 000 EUR
Maximum amount of support per project
250 000 EUR
Maximum aid intensity per project
Table 8: Maximum possible aid intensity by type of entity and type of research (Methodology: European Health Partnerships, p. 66)
Applicants
research organisation, enterprise
Duration of the project
48 months + 1 year (i.e. the project can be extended for one more year, but without the possibility to apply for additional funding during this period).
Deadlines for submission of project proposals:
Pre-proposals: 28.1.2025
Full proposals: 17.6.2025
Interested parties can attend the international information webinar on 27 November, 2024, 14:30 - 16:30 CET - Connection link (access code: 177383)
DOCUMENTS
Documents for Czech applicants
Conditions for the Czech bidder's participation in IICS Call 2025
Methodology: European Partnerships for Health
Sub-programme 3: European Partnerships in Health - effective from 22.5.2024
Mandatory attachments of the Czech applicant for Phase 1 (pre-proposals)
Affidavit of the applicant - Sworn statement of the applicant
Affidavit of the composition of the consortium
AZV ČR Application Form_Partnership ERA4Health IICS Call 2025
Mandatory annexes of the Czech applicant for Phase 2 (full proposals)
Documents on professional competence according to the nature of the project;
Updated budget table (AZV ČR Application Form).
Other documents
Definition of the type of results
Support contract_ERA4Health IICS Call 2025
The official call documents are available here
INFORMATION ABOUT THE CALL
The ERA4Health Partnership's pilot call for clinical trials, "Fostering Pragmatic Comparative-Effectiveness Trials in Non-communicable Diseases" (EffecTrial), aims to:
- Support randomized, interventional and pragmatic "comparative-effectiveness" studies in multiple countries
- Enable transnational collaboration between clinical/public health research teams conducting comparative effectiveness studies in multiple countries.
Project proposals should cover all 4 of the following topics:
- Be a pragmatic "comparative effectiveness trials" designed as a randomized intervention trial.
- Compare the use of currently approved health interventions either with each other or with the current standard of care.
- Take into account health interventions that may include, but are not limited to: diagnostic, screening, preventive and curative interventions. Interventions can be pharmacological and non-pharmacological practices such as nutrition and/or lifestyle, surgical interventions, prognostic methods, use of medical devices, e-health, as well as other health interventions.
- These interventions need to be of high relevance to the public only in the areas of these specific diseases (which are equally important):
- Cardiovascular disease;
- Metabolic disorders;
- Nutrition and lifestyle-related diseases;
- Non-communicable respiratory diseases.
Clinical trials initiated by investigators from multiple countries should primarily focus on at least one of these topics or a combination of them.
Size of the project consortium:
The number of participants and their research contribution should be appropriate to the objectives of the IICS and should be reasonably balanced in terms of international participation. Each project should represent a critical mass for achieving the ambitious scientific objectives and should clearly demonstrate the added value derived from collaborative work.
A minimum of 3 and a maximum of 5 countries should be represented in the consortium (this number does not include the countries of the collaborators (see below for the original text)).
| Number of countries in the consortium | 3-5 | 6 | 7 |
| Number of underrepresented countries in the consortium | No constraints | At least 1 | At least 2 |
| Maximum number of collaborators (be aware it corresponds to organisations not countries) | 3 | 3 | 3 |
List of participating countries:
Austria (FWF), Czech Republic (MZCR/AZVCR), France (Fr-MoH), Germany (BMBF/DLR), Ireland (HRB), Israel (CSO-MOH), Italy (IT-MOH), Latvia (LCS), Lithuania (LMT), Norway (RCN), Poland (NCBR), Slovakia (SAS), Spain (ISCIII, CSCJA)
*The list of participating countries is current as of 20.11.2024.
Call rules:
The call is governed by transnational rules common to applicants from all participating countries. In addition to the transnational rules, Czech applicants must also comply with the national conditions set by the relevant national provider. Applicants participating in applied research projects will therefore have to comply with national conditions based on Sub-programme 3: European Partnerships in Health.
Contact person
Mgr. Monika Kocmanová
Email:
Tel: + 420 606 273 871
You can also submit questions about the transnational call via email: .